翻訳と辞書 Words near each other ・ Malassezia ・ Malassezia caprae ・ Malassezia dermatis ・ Malassezia equina ・ Malassezia japonica ・ Malassezia nana ・ Malassezia pachydermatis ・ Malassezia sympodialis ・ Malat ・ MALAT1 ・ MALAT1-associated small cytoplasmic RNA ・ Malatang ・ Malataverne ・ Malate Catholic School ・ Malate Church ・ Malate dehydrogenase ・ Malate dehydrogenase (decarboxylating) ・ Malate dehydrogenase (disambiguation) ・ Malate dehydrogenase (NAD(P)+) ・ Malate dehydrogenase (NADP+) ・ Malate dehydrogenase (oxaloacetate-decarboxylating) ・ Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) ・ Malate dehydrogenase (quinone) ・ Malate dehydrogenase 2 ・ Malate oxidase ・ Malate synthase ・ Malate, Manila ・ Malate-aspartate shuttle ・ Malateh ・ Malatesta Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Malate dehydrogenase ： ウィキペディア英語版 Malate dehydrogenase Malate dehydrogenase () (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH. This reaction is part of many metabolic pathways, including the citric acid cycle. Other malate dehydrogenases, which have other EC numbers and catalyze other reactions oxidizing malate, have qualified names like malate dehydrogenase (NADP+). Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondrial membrane. Once in the cytosol, the malate is oxidized back to oxaloacetate by cytosolic malate dehydrogenase. Finally, phosphoenolpyruvate carboxykinase (PEPCK) converts oxaloacetate to phosphoenolpyruvate (PEP). == Isozymes == Several isozymes of malate dehydrogenase exist. There are two main isoforms in eukaryotic cells. One is found in the mitochondrial matrix, participating as a key enzyme in the citric acid cycle that catalyzes the oxidation of malate. The other is found in the cytoplasm, assisting the malate-aspartate shuttle with exchanging reducing equivalents so that malate can pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Humans and most other mammals express the following two malate dehydrogenases: 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Malate dehydrogenase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.